Concept:
Investigation of an epidemic follows a systematic sequence to identify the cause, affected population, and methods of control.
The major steps include:
• Verification and confirmation of epidemic
• Defining population at risk and case definition
• Data collection and hypothesis testing
• Laboratory confirmation of cause
This sequence helps identify the source and control the spread of disease.
Step 1: Identify the first step.
The first step is to verify whether an epidemic truly exists and confirm the diagnosis.
Thus, the first stage is:
\[
A \; (\text{Verification and Confirmation of epidemic})
\]
Step 2: Identify the second step.
After confirmation, the population at risk is identified and a valid case definition is developed.
Thus, the second stage is:
\[
C \; (\text{Defining population at risk and developing valid case definition})
\]
Step 3: Identify the third step.
Next, information is collected, hypotheses are formulated, and tested epidemiologically.
Thus, the third stage is:
\[
B \; (\text{Collecting information, hypothesis formulation and testing})
\]
Step 4: Identify the final step.
Finally, laboratory proof establishes the causal relationship.
Thus, the last stage is:
\[
D \; (\text{Final laboratory proof of cause and effect relationship})
\]
Step 5: Determine the correct sequence.
Therefore, the correct order is:
\[
A \rightarrow C \rightarrow B \rightarrow D
\]
Hence, the correct answer is:
\[
\boxed{(C)\ A, C, B, D}
\]