Question:
CD59 marker of which disease
CD59 marker of which disease
Updated On: Jul 12, 2025
- PNH
- PTEN
- BRR
- Cowden syndrome
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The Correct Option is A
Solution and Explanation
The CD59 marker is associated with the disease Paroxysmal Nocturnal Hemoglobinuria (PNH). CD59 is a protein that regulates the complement system by inhibiting the formation of the membrane attack complex (MAC) on cell surfaces. In PNH, a genetic mutation affects the surface proteins that normally anchor CD59, leading to an increased susceptibility of red blood cells to be lysed by the complement system.
| Disease | Associated Marker |
|---|---|
| PNH | CD59 |
| PTEN | Not associated |
| BRR | Not associated |
| Cowden syndrome | Not associated |
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