Question:

Beta 2 receptors act via following secondary messenger

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Beta-2 receptors are Gs-coupled GPCRs -- consider which enzyme is activated by the Gs protein.
Updated On: Jun 23, 2026
  • Adenylate Cyclase
  • Tyrosine kinase receptors
  • TGF-beta receptors
  • Cytokine receptors
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The Correct Option is A

Solution and Explanation

Beta-2 adrenergic receptors are Gs-coupled GPCRs. Agonist binding activates Gs, which stimulates Adenylate Cyclase (Adenylyl Cyclase) to convert ATP to cAMP. cAMP activates PKA, producing the cellular response (bronchodilation, smooth muscle relaxation, glycogenolysis).

Distractors:
- Tyrosine kinase receptors: insulin, EGF, PDGF
- TGF-beta receptors: serine/threonine kinase, SMAD pathway
- Cytokine receptors: JAK/STAT pathway

Beta-2 receptors act via Adenylate Cyclase (cAMP pathway).
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