Question:

Assertion (A): The p53 gene is often called guardian angel of human genome. Reason (R): It inhibits the development of tumors.

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p53: Guards the genome by stopping tumors!
Updated On: Jun 10, 2026
  • Both (A) and (R) are true. (R) is the correct explanation for (A)
  • Both (A) and (R) are true. (R) is not the correct explanation for (A)
  • (A) is true. But (R) is false
  • (A) is false. But (R) is true
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The Correct Option is A

Solution and Explanation

Step 1: Concept
Tumor suppressor genes.

Step 2: Analysis
Assertion (A) is true: The p53 gene is nicknamed the "guardian angel of the genome" due to its role in DNA repair and apoptosis. Reason (R) is true: It functions as a tumor suppressor by inhibiting uncontrolled cell growth, directly explaining why it protects the genome.

Step 3: Conclusion
Both are true, and (R) is the explanation.

Final Answer: (A)
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