Question:
Assertion A: Local anesthetic 2.5% lignocaine and 2.5% Prilocaine are used in combination for dental application.
Reason R: In combination they make eutectic, which easily cross keratinized layer of intact skin.
Assertion A: Local anesthetic 2.5% lignocaine and 2.5% Prilocaine are used in combination for dental application.
Reason R: In combination they make eutectic, which easily cross keratinized layer of intact skin.
Show Hint
EMLA = Eutectic Mixture of Local Anesthetics. It turns solids into a high-penetration liquid "oil."
Updated On: May 28, 2026
- Both A and R are correct and R is the correct explanation of A
- Both A and R are correct but R is NOT the correct explanation of A
- A is correct but R is not correct
- A is not correct but R is correct
Show Solution
Verified By Collegedunia
The Correct Option is A
Solution and Explanation
Step 1: Concept
This refers to the EMLA (Eutectic Mixture of Local Anesthetics) cream technology.
Step 2: Meaning
A eutectic mixture is a mixture of substances that melts at a lower temperature than any of its individual constituents.
Step 3: Analysis
Lignocaine and Prilocaine, when mixed in equal parts (2.5% each), form a liquid oil at room temperature. This liquid state allows for higher drug concentration and significantly better penetration through the skin's keratinized layers compared to individual components.
Step 4: Conclusion
Both statements are true, and the formation of the eutectic mixture is the direct reason for the enhanced penetration.
Final Answer: (A)
This refers to the EMLA (Eutectic Mixture of Local Anesthetics) cream technology.
Step 2: Meaning
A eutectic mixture is a mixture of substances that melts at a lower temperature than any of its individual constituents.
Step 3: Analysis
Lignocaine and Prilocaine, when mixed in equal parts (2.5% each), form a liquid oil at room temperature. This liquid state allows for higher drug concentration and significantly better penetration through the skin's keratinized layers compared to individual components.
Step 4: Conclusion
Both statements are true, and the formation of the eutectic mixture is the direct reason for the enhanced penetration.
Final Answer: (A)
Was this answer helpful?
0
0
Top CUET PG Pharmacy Questions
- Give below are two statements: One is labelled as Assertion A and the other is labelled as Reason R:
Assertion A: The presence of molecular forces produces a tendancy for individual solid particles to stick to each other and to other surface.
Reason R: Adhesion and cohesion can be considered as two aspects of particle aggregation.
In the light of the above statements, choose the most appropriate answer from the options given below: - Give below are two statements: One is labelled as Assertion A and the other is labelled as Reason R:
Assertion A: Immunoelectrophoresis or RIA is the best method for the quantification of IgE.
Reason R: Ordinary electrophoresis does not identify the subgroups of immunoglobulins IgG, IgA, IgM. IgE.
In the light of the above statements, choose the most appropriate answer from the options given below : - Give below are two statements: One is labelled as Assertion A and the other is labelled as Reason R:
Assertion A: The modified Noyes - Whitney equation states that larger the surface area of a drug, higher is the dissolution rate.
Reason R: the surface area increases with decreasing particle size.
In the light of the above statements, choose the most appropriate answer from the options given below - Give below are two statements: One is labelled as Assertion A and the other is labelled as Reason R:
Assertion A: Haloperidol is a preferred drug for acute schizophrenia and Huntington's disease.
Reason R: Parenteral administration by intramuscular route is possible in acute cases
In the light of the above statements, choose the most appropriate answer from the options given below: - Match List I with List II
List I
(Oral anti-diabetic Agents)List II
(Mechanism of Action)A. Voglibose I. AMP Activator B. Metformin II. K Channel blockers C. Tolbutamide III. \(\alpha\)-glucosidase Inhibitor D. Pioglitazone IV. PPAR-\(\gamma\) (gamma) activators
Choose the correct answer from the options given below:
View More Questions
Top CUET PG Clinical Pharmacy Questions
- Select the correct pair of globulins and drug with which they show binding:
- Match the LIST-I (Drug Combination) with LIST-II (Interaction): [H] {|l|l|l|l|} \multicolumn{2}{|c|}{LIST-I & \multicolumn{2}{c|}{LIST-II
\multicolumn{2}{|c|}{(Drug Combination) & \multicolumn{2}{c|}{(Interaction)
A. & Penicillamine: Aluminum containing antacids & I. & Decreased plasma level
B. & Lithium carbonate: Atropine & II. & Delayed gastric emptying
C. & Oral contraceptives: Ampicillin & III. & Formulation of poorly soluble complex
D. & Amitriptyline: Phenobarbitone & IV. & Decreased reabsorption of drug
- Oral absorption of drugs in neonate compared to older children and adults:
Top CUET PG Questions
- Given below are two statements:
Statement I: For Plato the meaning of the word 'Justice' is basically a conception in the mind only.
Statement II: For Plato the meaning of the word 'Justice' is fixed, mind-independently
In the light of the above statements, choose the correct answer from the options given below: - What is the electron count of OS6CO182-?
- XeF4 hydrolysis gives A + B, HF, and Oxygen. Find A and B
- What is more basic in pyrol and pyridine?
- Hydrolysis of Al2C3, Be2?
View More Questions