Question

Assertion A: Compression distillation is conducted at high pressure and temperature. Reason R: It produces pyrogen free water hence popular in pharmaceutical industries.

• A. Both A and R are correct and R is the correct explanation of A
• B. Both A and R are correct but R is NOT the correct explanation of A
• C. A is correct but R is not correct
• D. A is not correct but R is correct

Hint:

Distillation = Purification. Compression Distillation = High Efficiency + Pyrogen-free WFI.

Answer 1

The Correct Option is A

Step 1: Concept
Compression distillation (Vapor Compression Distillation) is a method used to produce Water for Injection (WFI).

Step 2: Meaning
It involves compressing water vapor to raise its temperature and pressure, which allows the latent heat of condensation to be used for evaporating more water.

Step 3: Analysis
Assertion A is correct as high pressure and temperature are fundamental to the compression cycle. Reason R is also correct; the primary purpose of this efficient process in pharma is to produce high-purity, pyrogen-free water. Because the process occurs at high temperatures, it ensures the destruction of pyrogens.

Step 4: Conclusion
Both statements are true, and the ability to produce sterile, pyrogen-free water at scale is why the high-pressure/temp process is utilized.

Final Answer: (A)