Question

Arrange common antigens as per their molecular weight A. Bovine gamma globulin (BGG) B. Ovalbumin (OVA) C. Bovine serum albumin (BSA) D. Sperm whale myoglobin (SWM) Choose the correct answer from the options given below:

• A. A$\rightarrow$B$\rightarrow$C$\rightarrow$D
• B. A$\rightarrow$C$\rightarrow$B$\rightarrow$D
• C. B$\rightarrow$C$\rightarrow$A$\rightarrow$D
• D. C$\rightarrow$D$\rightarrow$B$\rightarrow$A

Hint:

Higher molecular weight antigens generally produce stronger immune responses.

Answer 1

The Correct Option is B

Concept: Antigens differ in molecular weight and immunogenicity. Approximate molecular weights:
• BGG \( \approx 150000 \)
• BSA \( \approx 69000 \)
• OVA \( \approx 45000 \)
• SWM \( \approx 17000 \)

Step 1: Identify largest molecular weight antigen. Bovine gamma globulin: \[ \boxed{ \text{BGG} } \] has highest molecular weight. Thus: \[ \boxed{A} \] comes first.

Step 2: Compare BSA and OVA. BSA molecular weight: \[ 69000 \] OVA molecular weight: \[ 45000 \] Hence: \[ \boxed{ \text{BSA} > \text{OVA} } \] Therefore: \[ \boxed{C} \] comes before: \[ \boxed{B} \]

Step 3: Identify smallest molecular weight antigen. Sperm whale myoglobin has smallest molecular weight. Thus: \[ \boxed{D} \] comes last.

Step 4: Write complete arrangement. Hence order becomes: \[ \boxed{ A \rightarrow C \rightarrow B \rightarrow D } \] Therefore correct answer is: \[ \boxed{(2)} \] Final Conclusion: Correct decreasing molecular weight order: \[ \boxed{ \text{BGG} > \text{BSA} > \text{OVA} > \text{SWM} } \]