Step 1: Understanding the Concept
Chromosomal number changes can be euploidy (whole sets) or aneuploidy.
Step 2: Definition
Aneuploidy is the gain or loss of one or more chromosomes, as in Down syndrome (trisomy 21) and Turner syndrome.
Step 3: Compare the options
Addition of a whole set is polyploidy, and haploid and tetraploid sets are euploid conditions. The first option defines aneuploidy.
Final Answer:
Aneuploidy is addition or deletion of one or more chromosomes to the total number.
\[ \boxed{\text{(A) }\text{addition or deletion of one or more chromosomes to the total number.}} \]