Question:
Aneuploidy is a chromosomal disorder where chromosome number is not the exact copy of its haploid set of chromosomes, due to :
(a) Substitution
(b) Addition
(c) Deletion
(d) Translocation
(e) Inversion
Choose the most appropriate answer from the options given below
Aneuploidy is a chromosomal disorder where chromosome number is not the exact copy of its haploid set of chromosomes, due to :
(a) Substitution
(b) Addition
(c) Deletion
(d) Translocation
(e) Inversion
Choose the most appropriate answer from the options given below
(a) Substitution
(b) Addition
(c) Deletion
(d) Translocation
(e) Inversion
Choose the most appropriate answer from the options given below
Updated On: May 1, 2026
- (c) and (d) only
- (d) and (e) only
- (a) and (b) only
- (b) and (c) only
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The Correct Option is D
Solution and Explanation
Aneuploidy is a type of chromosomal disorder where the number of chromosomes is not an exact multiple of the haploid set. This is primarily caused by the addition or deletion of chromosomes rather than changes involving substitution, translocation, or inversion of chromosome sections. Let us explore why options (b) and (c) are the correct answer for this question.
- Understanding Aneuploidy: Aneuploidy refers to a numerical change in part of the chromosome set. This means there can be either more chromosomes than usual (addition) or fewer (deletion).
-
Option Analysis:
- (a) Substitution: This does not cause a change in the number of chromosomes but rather might change the gene sequence within a chromosome.
- (b) Addition: This leads to an increase in the number of chromosomes, causing aneuploidy. For example, trisomy, where there is an extra chromosome (like in Down syndrome, which is trisomy 21).
- (c) Deletion: This results in a decrease in the number of chromosomes, and it is another form of aneuploidy. An example is monosomy, where one chromosome is missing.
- (d) Translocation: Although it involves the rearrangement of chromosomes, it does not typically change the chromosome number.
- (e) Inversion: This involves rotation of a chromosome segment and does not affect the number of chromosomes.
- Conclusion: Since aneuploidy results from changes in chromosome number, which involves addition and deletion, the most appropriate answer is (b) and (c) only.
In conclusion, aneuploidy is directly related to changes in chromosome number through addition and deletion, not through rearrangement or substitution of chromosome parts.
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