Question:
Allergy is caused due to the release of chemicals like:
Allergy is caused due to the release of chemicals like:
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Antihistamines are commonly used to treat allergies because they block the receptors for histamine, which is the chief mediator of allergic symptoms.
Updated On: Jul 22, 2026
- Ovaprim, Epinephrine
- Dopamine, Acetyl choline
- Histamine, Serotonin
- Gama Amino Butyric Acid, Glycine
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The Correct Option is C
Solution and Explanation
Step 1: Understanding the Question:
This question asks for the identity of the chemical mediators responsible for producing the symptoms of an allergic reaction.
Step 2: Key Concept and Approach:
Allergy is a hypersensitivity reaction of the immune system to environmental antigens.
It is mediated by IgE antibodies, which bind to mast cells and basophils.
Upon re-exposure to the allergen, mast cells undergo degranulation, releasing vasoactive inflammatory mediators.
Step 3: Detailed Explanation:
• Histamine and Serotonin: These are the primary chemicals stored in mast cell granules.
Histamine causes vasodilation, increases vascular permeability, and causes bronchoconstriction.
Serotonin also acts as a vasodilator and increases capillary permeability, contributing to tissue redness and swelling.
Hence, Option (C) is correct.
• Epinephrine: This hormone actually counteracts allergic reactions (by causing bronchodilation and vasoconstriction) and is used to treat anaphylaxis.
• Dopamine, Acetylcholine, GABA, and Glycine: These are primarily nervous system neurotransmitters and are not the primary mediators of inflammatory allergic reactions.
Step 4: Final Answer:
Allergy symptoms are caused by the release of histamine and serotonin from mast cells.
This question asks for the identity of the chemical mediators responsible for producing the symptoms of an allergic reaction.
Step 2: Key Concept and Approach:
Allergy is a hypersensitivity reaction of the immune system to environmental antigens.
It is mediated by IgE antibodies, which bind to mast cells and basophils.
Upon re-exposure to the allergen, mast cells undergo degranulation, releasing vasoactive inflammatory mediators.
Step 3: Detailed Explanation:
• Histamine and Serotonin: These are the primary chemicals stored in mast cell granules.
Histamine causes vasodilation, increases vascular permeability, and causes bronchoconstriction.
Serotonin also acts as a vasodilator and increases capillary permeability, contributing to tissue redness and swelling.
Hence, Option (C) is correct.
• Epinephrine: This hormone actually counteracts allergic reactions (by causing bronchodilation and vasoconstriction) and is used to treat anaphylaxis.
• Dopamine, Acetylcholine, GABA, and Glycine: These are primarily nervous system neurotransmitters and are not the primary mediators of inflammatory allergic reactions.
Step 4: Final Answer:
Allergy symptoms are caused by the release of histamine and serotonin from mast cells.
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