Question:
All of the following are correct about a molecule designated as cytochrome P450 except it:
All of the following are correct about a molecule designated as cytochrome P450 except it:
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"P450" refers to the absorption peak at 450 nm when bound to CO. They are a "Superfamily," not just one family!
Updated On: May 28, 2026
- Comes from the same gene family as all other cytochrome P450
- May accept electrons from substance such as NADPH
- Contains heme as a prosthetic group
- Catalyses the hydroxylation of a hydrophobic substance
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The Correct Option is A
Solution and Explanation
Step 1: Concept
Cytochrome P450 (CYP) is a superfamily of enzymes involved in drug metabolism.
Step 2: Meaning
These enzymes catalyze monooxygenation reactions.
Step 3: Analysis
CYP enzymes contain heme (C). They require electrons from NADPH via a reductase (B). Their primary role is hydroxylating hydrophobic (lipophilic) drugs (D). However, they do NOT all come from the same *gene* family; they come from a *superfamily* divided into many different families (e.g., CYP1, CYP2, CYP3).
Step 4: Conclusion
Option A is incorrect because "same gene family" is too narrow for this diverse superfamily.
Final Answer: (A)
Cytochrome P450 (CYP) is a superfamily of enzymes involved in drug metabolism.
Step 2: Meaning
These enzymes catalyze monooxygenation reactions.
Step 3: Analysis
CYP enzymes contain heme (C). They require electrons from NADPH via a reductase (B). Their primary role is hydroxylating hydrophobic (lipophilic) drugs (D). However, they do NOT all come from the same *gene* family; they come from a *superfamily* divided into many different families (e.g., CYP1, CYP2, CYP3).
Step 4: Conclusion
Option A is incorrect because "same gene family" is too narrow for this diverse superfamily.
Final Answer: (A)
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