Question:
Acute Renal failure can be detected biochemically by elevated level of which of the following components of serum?
Acute Renal failure can be detected biochemically by elevated level of which of the following components of serum?
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A substance cleared by glomerular filtration piles up in serum when filtration falls.
Updated On: Nov 12, 2026
- Ammonia
- Albumin
- Bile Salts
- Creatinine
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The Correct Option is D
Solution and Explanation
Step 1: Understanding the Concept
Creatinine is formed from muscle creatine at a steady rate and is cleared mainly by glomerular filtration.
Step 2: In acute renal failure
The filtration rate falls suddenly, so creatinine builds up in the serum along with urea.
Step 3: Why the other options fail
High ammonia points to liver failure and bile salts to liver or bile duct disease. Serum albumin tends to fall, not rise, in kidney disease.
Final Answer:
Acute renal failure shows as an elevated serum creatinine level. \[ \boxed{\text{(D) }\text{Creatinine}} \]
Creatinine is formed from muscle creatine at a steady rate and is cleared mainly by glomerular filtration.
Step 2: In acute renal failure
The filtration rate falls suddenly, so creatinine builds up in the serum along with urea.
Step 3: Why the other options fail
High ammonia points to liver failure and bile salts to liver or bile duct disease. Serum albumin tends to fall, not rise, in kidney disease.
Final Answer:
Acute renal failure shows as an elevated serum creatinine level. \[ \boxed{\text{(D) }\text{Creatinine}} \]
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