Question

Acute renal failure can be detected biochemically by -------------------.

• A. Elevated level of amino acids.
• B. Lower level of uric acid.
• C. Elevated level of serum creatinine.
• D. Lower level of serum creatinine.

Hint:

Creatinine is cleared by filtration, so when filtration fails its level in blood rises.

Answer 1

The Correct Option is C

Step 1: Understanding the Concept
Creatinine is a waste formed from muscle creatine and removed from blood by glomerular filtration.

Step 2: In renal failure
In acute renal failure the glomerular filtration rate drops suddenly.
Creatinine and urea then build up in the blood.

Step 3: Conclusion
A raised serum creatinine level indicates acute renal failure; a low level does not.

Final Answer:
Elevated serum creatinine detects acute renal failure. \[ \boxed{\text{(C) }\text{Elevated level of serum creatinine.}} \]