Step 1: Understanding the Concept
The Central Pollution Control Board identifies fine particulate matter of diameter \(2.5\ \mu\text{m}\) or less (PM 2.5) as the most harmful to human health.
Step 2: Why harmful
Such particles pass deep into the lungs up to the alveoli and cause breathing trouble, irritation, inflammation, lung damage and early death.
Step 3: Conclusion
Coarser particles are mostly trapped in the nose and upper airways. So the most harmful particles are \(2.5\ \mu\text{m}\) or less in diameter.
Final Answer:
Particles of 2.5 micrometre diameter or less are the most harmful.
\[ \boxed{\text{(A) }2.5\ \mu\text{m or less in diameter}} \]