Question

Absorption of Vitmain B₁₂ is facilitated by

• A. Hydrogel
• B. Glycoprotein
• C. Lipoprotein
• D. Microprotein

Answer 1

The Correct Option is B

The absorption of Vitamin B₁₂ is facilitated by a protein known as glycoprotein. To understand why glycoprotein is the correct answer, let's delve into the role it plays in the absorption process:

1. Role of Glycoprotein (Intrinsic Factor):
   • Vitamin B₁₂, also known as cobalamin, is a water-soluble vitamin essential for red blood cell formation, neurological function, and DNA synthesis.
   • In the stomach, Vitamin B₁₂ binds to a glycoprotein called Intrinsic Factor (IF) produced by the parietal cells of the gastric mucosa.
2. Mechanism of Absorption:
   • The B₁₂-Intrinsic Factor complex travels to the ileum, which is the last part of the small intestine.
   • Here, specific receptors recognize and bind to the complex, allowing the absorption of Vitamin B₁₂ into the bloodstream.
3. Exclusion of Other Options:
   • Hydrogel, Lipoprotein, and Microprotein are not involved in the absorption of Vitamin B₁₂. Hydrogel refers to a network of polymer chains, lipoproteins are molecules made of proteins and fats, and microproteins are small protein or peptide molecules, none of which facilitate the absorption of vitamin B₁₂.

In conclusion, glycoprotein, specifically the Intrinsic Factor, is crucial for the absorption of Vitamin B₁₂ in the human body. Without it, absorption is impaired, leading to possible deficiencies such as pernicious anemia.