Question:
A commonly used Anticoagulant for blood glucose estimation is
A commonly used Anticoagulant for blood glucose estimation is
Show Hint
Associate "blood glucose estimation" with Sodium fluoride (Gray top tube), which preserves glucose levels by blocking the glycolytic enzyme enolase.
Updated On: Jul 8, 2026
- EDTA
- Sodium citrate
- Heparin
- Sodium fluoride
Show Solution
Verified By Collegedunia
The Correct Option is D
Solution and Explanation
Step 1: Understanding the Concept:
Following blood collection, red blood cells continue to metabolize glucose via glycolysis, which artificialy decreases the measured glucose concentration over time.
To obtain an accurate reading, an agent must be used that inhibits glycolysis in addition to preventing coagulation.
Step 3: Detailed Explanation:
- Sodium fluoride acts as an antiglycolytic agent by inhibiting enolase, a key enzyme in the glycolytic pathway. It is commonly paired with potassium oxalate (an anticoagulant) in clinical gray-top blood collection tubes.
- EDTA and Sodium citrate prevent coagulation by chelating calcium ions but do not halt cellular glycolysis.
- Heparin acts by activating antithrombin III to inhibit coagulation pathways but does not affect glycolytic enzymes.
Step 4: Final Answer
The agent used to preserve blood samples for glucose estimation is sodium fluoride.
Following blood collection, red blood cells continue to metabolize glucose via glycolysis, which artificialy decreases the measured glucose concentration over time.
To obtain an accurate reading, an agent must be used that inhibits glycolysis in addition to preventing coagulation.
Step 3: Detailed Explanation:
- Sodium fluoride acts as an antiglycolytic agent by inhibiting enolase, a key enzyme in the glycolytic pathway. It is commonly paired with potassium oxalate (an anticoagulant) in clinical gray-top blood collection tubes.
- EDTA and Sodium citrate prevent coagulation by chelating calcium ions but do not halt cellular glycolysis.
- Heparin acts by activating antithrombin III to inhibit coagulation pathways but does not affect glycolytic enzymes.
Step 4: Final Answer
The agent used to preserve blood samples for glucose estimation is sodium fluoride.
Was this answer helpful?
0
0
Top ICAR AIEEA Animal Science Questions
- Which of the following antiviral drug is available for treatment of lumpy skin disease in cow?
- How do you arrange the correct sequence of the following procedural steps for early pregnancy diagnosis in cow?
(A) Do the insemination in adult dairy cows.
(B) Administer a small dose (2.5 mg or 0.5 ml) of Dinoprost (Lutalyse) intravenously through the ear vein.
(C) Observe critically the teat of the animal for alveolar milk to start flowing about one minute later.
(D) After 18 to 22 days and 3 hours prior to the evening milking, place the teat cannula in the left fore-teat and leave it for milk flow from the teat cistern till it ceases.
Choose the correct answer from the options given below which describe the correct sequential steps for early pregnancy diagnosis in cow. - Match List-I with List-II.Choose the correct answer from the options given below.
List-I (Toxic Element) List-II (Effect of toxicity on Animal) (A) Fluoride (I) Abdominal pain and diarrhea can be common clinical signs in animals exposed. (B) Arsenic (II) Short-term exposure may include nausea, vomiting, diarrhea, increase in blood pressure or heart rate, skin rashes and eye irritation. (C) Lead (III) Cattle can show clinical signs of depression, weakness and ataxia with postmortem findings of gastroenteritis and degenerative changes in the renal tubular epithelium. (D) Mercury (IV) Abdominal pain or colic, vomiting, a staggering gait and weakness, incoordination, rapid weak pulse and shock, diarrhea, followed by collapse and death. - Polygene term was given by one of the following?
- According to Hardy Weinberg Law, genotype frequencies in the progeny depend only on the
View More Questions
Top ICAR AIEEA Food and Nutrition Questions
- Which of the following is an essential fatty acid for animals?
- The crude protein of the animal feeds can be calculated by multiplying the nitrogen content with which of the following factors?
- Glycogens are present in which of the following?
- The proportion of which volatile fatty acid will be higher in the rumen of animals fed on a high roughage diet?
- The precursor of vitamin D3 for animals is:
View More Questions
Top ICAR AIEEA Questions
- Which of the following statements is false?
- Which of the following is an example of an inventory?
- According to Adam Smith, productivity gains could be brought about through .
- The supply curve for an artificially scarce good is .
- Which of the following would not be considered an opportunity cost of paid employment?
View More Questions