Question:
A 15 year old boy presents with cough, sneezing and bronchoconstriction. His shows eosinophilia. This condition is most likely associated with which type of hypersensitivity reaction
A 15 year old boy presents with cough, sneezing and bronchoconstriction. His shows eosinophilia. This condition is most likely associated with which type of hypersensitivity reaction
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Type I = Allergic (IgE), Type II = Cytotoxic (IgG), Type III = Immune Complex, Type IV = Delayed (T-cells).
Updated On: May 25, 2026
- IgE-mediated hypersensitivity
- IgG-mediated cytotoxic hypersensitivity
- Immune complex-mediated hypersensitivity
- Delayed-type hypersensitivity
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The Correct Option is A
Solution and Explanation
Step 1: Concept
Hypersensitivity reactions are exaggerated immune responses to an antigen. Type I is the immediate type.
Step 2: Meaning
Bronchoconstriction and sneezing in the presence of eosinophilia are classic hallmarks of allergic asthma or hay fever.
Step 3: Analysis
These symptoms occur when an allergen cross-links IgE antibodies on the surface of mast cells, leading to the release of histamine and leukotrienes. Eosinophils are typically recruited in the late-phase response of Type I reactions.
Step 4: Conclusion
The clinical presentation clearly points to Type I, which is IgE-mediated. Final Answer: (A)
Hypersensitivity reactions are exaggerated immune responses to an antigen. Type I is the immediate type.
Step 2: Meaning
Bronchoconstriction and sneezing in the presence of eosinophilia are classic hallmarks of allergic asthma or hay fever.
Step 3: Analysis
These symptoms occur when an allergen cross-links IgE antibodies on the surface of mast cells, leading to the release of histamine and leukotrienes. Eosinophils are typically recruited in the late-phase response of Type I reactions.
Step 4: Conclusion
The clinical presentation clearly points to Type I, which is IgE-mediated. Final Answer: (A)
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