List of top Medical Questions

TH2 inflammation is mediated by which of the following cytokines?
Which of the following disorders is most commonly linked with ischemic stroke caused by a hypercoagulable (prothrombotic) state?
A patient with acute graft-versus-host disease (GVHD) following allogeneic stem cell transplantation shows no clinical improvement despite treatment with high-dose corticosteroids. Which of the following is the next best drug to use?
Identify the genetic condition from the image shown below
A patient previously operated for parathyroid adenoma presents with abdominal pain, dyspepsia, and gastrin level of 600 pg/mL. Endoscopy shows multiple duodenal nodules with raised mucosal folds. What is the next step in management?
A 52-year-old male with type 2 diabetes mellitus presents with hypertension and proteinuria. His serum creatinine is 1.4 mg/dL and estimated GFR is 65 mL/min/1.73 m$^2$. Which of the following classes of drugs is most appropriate for renal protection in this patient?
An elderly male chronic smoker presents with dyspnea. His FEV1/FVC ratio is 65% and FEV1 is 55% of predicted. According to GOLD criteria he falls into which class?
A cachectic 65-year-old male hospitalized with community-acquired pneumonia has severe weight loss and muscle wasting. His gastrointestinal function is intact. Which of the following is the best nutritional support strategy for this patient?
A patient with Cushing’s disease underwent bilateral adrenalectomy and presents 10 years later with hyperpigmentation. Which of the following statements is false regarding this condition?
A patient presents with fatigue, weight loss, polyuria, low sodium, low cortisol, and joint pain. Serum calcium, ESR, and TSH are normal. What is the likely diagnosis?
A female with cyclical abdominal pain, diabetes mellitus onset at age 10, and chronic kidney disease by age 18, with a family history of diabetes and uterine malformation, presents a clinical pattern characteristic of which diagnosis?
Patient with trigeminal neuralgia and focal seizures started on oxcarbamazepine, which of the following conditions would you monitor for in this patient.
A 5-year-old boy presents with short stature, facial dysmorphism, pulmonary valve stenosis, and features suggestive of Noonan syndrome. His parents ask about the genetic basis of the disease. What should they be counseled regarding gene mutation and inheritance?
A 17-year-old girl presents with short stature, delayed puberty, and primary amenorrhea. She also has poor vision due to bilateral optic atrophy. On examination, her visual acuity is reduced. What is the most probable diagnosis?
A 34-year-old male presents with episodic palpitations, hypertension, and ataxia. Urinary studies show very high normetanephrine but normal metanephrine. CT abdomen reveals a large adrenal mass. What is the most likely underlying syndrome?
Which of the following hormones has the longest half-life (t½)?
A patient with 3 months of polyuria has serum osmolality of 280, urine osmolality of 300, serum sodium 140, and no nocturnal polyuria, no H/o previous medications. What is the most likely diagnosis?
A 16-year-old phenotypic female with hypertension and hypokalemia presents with primary amenorrhea and lack of secondary sexual characteristics. Karyotype reveals 46,XY. Which of the following enzyme deficiencies is most likely?
A 30-year-old woman presents with amenorrhea, oral candidiasis, and features of adrenal insufficiency. Laboratory findings show elevated FSH level as 27IU/L. Which gene mutation is most likely responsible for this condition?
A patient has completed treatment for H. pylori infection. Which of the following statements regarding follow-up testing is true?
A 58-year-old man presents with fever, jaundice, and right upper quadrant pain. Laboratory results show elevated bilirubin and alkaline phosphatase. Ultrasound reveals a dilated common bile duct with suspected stones 3-4m . Which of the following is the best diagnostic and therapeutic procedure for this patient?
A patient with chronic liver disease presents with abdominal distention and jaundice. Upper GI endoscopy reveals non-bleeding varices. What is the drug of choice for primary prophylaxis?
A 56-year-old man presents with left lower quadrant abdominal pain, fever, and leukocytosis. CT abdomen reveals acute sigmoid diverticulitis with a 3 cm pericolic abscess. What is the most appropriate first step in management?
A patient with ulcerative colitis on mesalazine 2.4 g/day (MAYO score 1) in remission presents with bloody diarrhoea for the past 3–4 days. What is the next best step in management?
A 52-year-old man with a history of alcoholic cirrhosis presents with massive upper gastrointestinal bleeding. Endoscopy reveals actively bleeding gastric varices that do not respond to cyanoacrylate (glue) injection. What is the next best step in management?