Question

Write a short note on any three chromosomal aberrations (syndromes) found in humans.

Hint:

Remember: Down’s (21 trisomy), Klinefelter’s (XXY), Turner’s (XO); each affects growth and development. % Topic Human Genetics

Answer 1

1. Down’s Syndrome: Trisomy of chromosome 21, causing mental retardation and characteristic facial features.
2. Klinefelter’s Syndrome: Males with an extra X chromosome (XXY), leading to reduced fertility and feminine characteristics.
3. Turner’s Syndrome: Females with a single X chromosome (XO), leading to short stature and lack of sexual development.