With respect to drug-enzyme interaction, identify the wrong statement.
Show Hint
- Allosteric inhibitor changes the enzyme's active site
- Allosteric inhibitor competes with the enzyme's active site
- Competitive inhibitor binds to the enzyme's active site
- Non-Competitive inhibitor binds to the allosteric site
The Correct Option is B
Solution and Explanation
Allosteric (non-competitive) inhibitors bind at a different (allosteric) site, which changes the shape of the active site so that the substrate cannot bind: statements (1) and (4) are correct.
Statement (2) says the allosteric inhibitor competes with the active site, which is wrong since it binds elsewhere.
Answer: (2) Allosteric inhibitor competes with the enzyme's active site
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