Question:
Which organism causes lymphogranuloma venereum (LGV)?
Which organism causes lymphogranuloma venereum (LGV)?
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Same genus as trachoma and genital chlamydia, but the L-serovars give a bubo-forming lymphatic disease.
Updated On: Jun 23, 2026
- Chlamydia trachomatis
- Neisseria gonorrhoeae
- Treponema pallidum
- Haemophilus ducreyi
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The Correct Option is A
Solution and Explanation
Answer: Chlamydia trachomatis.
Step 1: Lymphogranuloma venereum is a chronic sexually transmitted infection of the lymphatic system, presenting with a small painless genital ulcer followed by painful inguinal buboes (the groove sign).
Step 2: It is caused by Chlamydia trachomatis serovars L1, L2 and L3. These differ from the serovars (D to K) that cause ordinary genital chlamydia and from those (A to C) that cause trachoma.
Step 3: The distractors cause different STDs: Neisseria gonorrhoeae causes gonorrhoea, Treponema pallidum causes syphilis, and Haemophilus ducreyi causes chancroid. Diagnosis of LGV uses nucleic acid testing for C. trachomatis with serovar typing.
Ref: Lange Review of Medical Microbiology and Immunology, 14e, p. 208.
Step 1: Lymphogranuloma venereum is a chronic sexually transmitted infection of the lymphatic system, presenting with a small painless genital ulcer followed by painful inguinal buboes (the groove sign).
Step 2: It is caused by Chlamydia trachomatis serovars L1, L2 and L3. These differ from the serovars (D to K) that cause ordinary genital chlamydia and from those (A to C) that cause trachoma.
Step 3: The distractors cause different STDs: Neisseria gonorrhoeae causes gonorrhoea, Treponema pallidum causes syphilis, and Haemophilus ducreyi causes chancroid. Diagnosis of LGV uses nucleic acid testing for C. trachomatis with serovar typing.
Ref: Lange Review of Medical Microbiology and Immunology, 14e, p. 208.
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