Question:
Which one of the following shows allosteric inhibition ?
Which one of the following shows allosteric inhibition ?
Updated On: Jul 11, 2025
- Malonic acid & succinate
- 2, 3 BPG
- Amino acid alanine & pyruvate kinase
- Citrate
Show Solution
Verified By Collegedunia
The Correct Option is B
Solution and Explanation
In biochemical pathways, allosteric inhibition refers to the regulation of a protein by binding to a specific site other than the protein's active site. This process alters the protein's activity.
1. Malonic acid & succinate: Malonic acid acts as a competitive inhibitor of succinate dehydrogenase, not allosteric.
2. 2, 3 BPG: This binds to hemoglobin and decreases oxygen affinity, functioning as an allosteric inhibitor.
3. Amino acid alanine & pyruvate kinase: Alanine inhibits pyruvate kinase allosterically to decrease glycolysis when the cell does not need energy.
4. Citrate: Acts as an allosteric inhibitor in glycolysis but is not specifically described here as allosteric inhibition.
The correct answer showcasing a distinct mechanism of allosteric inhibition is 2, 3 BPG, as it distinctly alters the function of hemoglobin through allosteric mechanisms to regulate oxygen delivery.
Was this answer helpful?
0
0
Top NEET PG Biochemistry Questions
- A patient presents with xanthomas on the Achilles tendon. Which of the following is the most likely diagnosis?
- A patient with multiple tendon xanthomas is found to have a serum cholesterol level of 398 mg/dL and an LDL level of 220 mg/dL. What is the most likely defect?
A 23-year-old female with a height of 4 feet has a karyotype, as shown in the image below. Which of the following conditions is the most likely etiology?
- A patient presenting with bleeding gums and easy bruisability was diagnosed with scurvy. This is due to
- A child presents with bone pain and hepatosplenomegaly. A trephine biopsy and aspirate show the following finding. Which of the following is the most likely enzyme deficient in this condition?
View More Questions
Top NEET PG Concepts and regulation of metabolism of amino acids Questions
- A child presents to you with anemia, thrombocytopenia, and bony pain. On examination, hepatosplenomegaly was noticed. If light microscopy of bone marrow aspirate reveals “crumpled tissue paper” appearance, what is the enzyme defect?
- NEET (PG) - 2022
- Biochemistry
- Concepts and regulation of metabolism of amino acids
An adolescent male patient presents to you with exercise intolerance. He gives a history of developing cramps on exertion. Which of the following enzyme deficiencies could be the cause?
- NEET (PG) - 2022
- Biochemistry
- Concepts and regulation of metabolism of amino acids
- A patient from a Mediterranean country visits Africa, where he develops malaria. He is treated with primaquine and later develops hemolytic anemia. Deficiency of an enzyme involved in which of the following pathways could be the cause?
- NEET (PG) - 2022
- Biochemistry
- Concepts and regulation of metabolism of amino acids
- Addition of which Amino Acid will increase UV absorption
- NEET (PG)
- Biochemistry
- Concepts and regulation of metabolism of amino acids
- Which amino acid is used to synthesize Nitric oxide ?
- NEET (PG)
- Biochemistry
- Concepts and regulation of metabolism of amino acids
View More Questions
Top NEET PG Questions
Which of the following cranial nerves is responsible for the motor innervation of the muscles of mastication?
- NEET (PG) - 2025
- General Science
The normal pH of arterial blood is:
- NEET (PG) - 2025
- General Science
Which enzyme is deficient in Gaucher’s disease?
- NEET (PG) - 2025
- General Science
The anticoagulant effect of heparin is monitored using:
- NEET (PG) - 2025
- General Science
The causative agent of malaria is:
- NEET (PG) - 2025
- General Science
View More Questions