Question:
Which of the following types of cell death involves activation of caspase enzymes?
Which of the following types of cell death involves activation of caspase enzymes?
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Caspases are important in apoptosis and pyroptosis; necrosis is not caspase-mediated.
Updated On: May 14, 2026
- Necrosis and apoptosis
- Apoptosis and pyroptosis
- Apoptosis and necroptosis
- Apoptosis only
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The Correct Option is B
Solution and Explanation
Concept:
Caspases are proteolytic enzymes involved in programmed cell death. Apoptosis involves caspase activation, and pyroptosis is an inflammatory form of programmed cell death mediated by inflammatory caspases.
Step 1: Recall apoptosis.
Apoptosis involves activation of initiator and executioner caspases.
Step 2: Recall pyroptosis.
Pyroptosis is mediated by inflammatory caspases and is associated with inflammasome activation.
Step 3: Choose the correct combination.
Both apoptosis and pyroptosis involve caspase activation. Therefore, the correct answer is Apoptosis and pyroptosis.
Step 1: Recall apoptosis.
Apoptosis involves activation of initiator and executioner caspases.
Step 2: Recall pyroptosis.
Pyroptosis is mediated by inflammatory caspases and is associated with inflammasome activation.
Step 3: Choose the correct combination.
Both apoptosis and pyroptosis involve caspase activation. Therefore, the correct answer is Apoptosis and pyroptosis.
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