Question:
Which of the following statements are correct:
A. Phosphorylation of mannose residues is a critical step in sorting lysosomal proteins.
B. Phosphorylated mannose residues are recognized by a mannose-6-phosphate receptor in the cis Golgi network.
C. N-linked glycosylation takes place in both endoplasmic reticulum and Golgi body.
D. O-linked glycosylation occurs entirely in Golgi body.
Which of the following statements are correct:
A. Phosphorylation of mannose residues is a critical step in sorting lysosomal proteins.
B. Phosphorylated mannose residues are recognized by a mannose-6-phosphate receptor in the cis Golgi network.
C. N-linked glycosylation takes place in both endoplasmic reticulum and Golgi body.
D. O-linked glycosylation occurs entirely in Golgi body.
B. Phosphorylated mannose residues are recognized by a mannose-6-phosphate receptor in the cis Golgi network.
C. N-linked glycosylation takes place in both endoplasmic reticulum and Golgi body.
D. O-linked glycosylation occurs entirely in Golgi body.
Show Hint
M6P = Address for the Lysosome; âNâ starts in ER, âOâ happens in Golgi.
Updated On: May 28, 2026
- A, B and C Only
- A, C and D Only
- A, B and D Only
- A and C Only
Show Solution
Verified By Collegedunia
The Correct Option is B
Solution and Explanation
Step 1--3: Analysis
Statement A is true. Statement B is false: M6P receptors recognise the tag in the trans Golgi network, not cis. Statement C is true. Statement D is true.
Step 4: Conclusion
Statements A, C, and D are correct.
Final Answer: (B)
Statement A is true. Statement B is false: M6P receptors recognise the tag in the trans Golgi network, not cis. Statement C is true. Statement D is true.
Step 4: Conclusion
Statements A, C, and D are correct.
Final Answer: (B)
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