Question

Which of the following statements about antibodies is NOT correct?

• A. Human gamma globulins consist of at least 25 to 30 different proteins
• B. A typical immunoglobulin consists of 4 subunits
• C. Gamma globulins are formed predominantly by the liver
• D. Immunoglobulins have a molecular weight of about 1,50,000

Hint:

Think about which cells make antibodies, not which organ makes most other blood proteins.

Answer 1

The Correct Option is C

Step 1: Understanding the Question.
The question gives four statements about antibodies and asks which one is wrong.

Step 2: Key Concept.
Antibodies, also called immunoglobulins or gamma globulins, are proteins made by plasma cells, which come from B lymphocytes. The liver makes most other blood proteins, like albumin and clotting factors, but it does not make antibodies.

Step 3: Detailed Explanation.
Human gamma globulins do include a large family, at least 25 to 30 different proteins once you count all the immunoglobulin classes and subclasses. This statement is true.
A typical immunoglobulin, like IgG, is built from 4 protein chains, 2 heavy and 2 light, joined together. This statement is true.
Gamma globulins being formed predominantly by the liver is false. Plasma cells derived from B lymphocytes, not the liver, make antibodies. This is the wrong statement.
A typical immunoglobulin has a molecular weight close to 150,000, which is correct for IgG. This statement is true.

Step 4: Final Answer.
The statement that is NOT correct is that gamma globulins are formed predominantly by the liver.