Step 1: Understanding GM research regulation.
Genetically Modified (GM) crops and organisms require strict regulation to ensure their safety for humans, animals, and the environment.
Step 2: Role of GEAC.
The Genetic Engineering Appraisal Committee (GEAC) under the Ministry of Environment, Forest and Climate Change is the apex body that approves large-scale use, release, and commercial introduction of GM organisms in India.
Step 3: Analyzing options.
(A) Department of Science and Technology: Incorrect — This promotes science research but does not regulate GM organisms.
(B) Department of Biotechnology: Incorrect — It promotes biotech research but approval lies with GEAC.
(C) GEAC: Correct — Responsible for decisions about GM research validity and safety.
(D) Indian Patent Office: Incorrect — It deals with intellectual property rights, not biosafety.
Step 4: Conclusion.
Hence, the correct answer is GEAC.