Question

What is the use of alpha-1-antitrypsin?

• A. In treatment of emphysema
• B. In treatment of asthma
• C. As insecticidal protein
• D. In treatment of diabetes

Hint:

Alpha-1-antitrypsin deficiency can cause lung damage; supplementing it helps in emphysema management.

Answer 1

The Correct Option is A

Step 1: Understanding alpha-1-antitrypsin.
Alpha-1-antitrypsin is a glycoprotein that protects tissues from enzymes of inflammatory cells, especially elastase. A deficiency of this protein causes damage to lung tissues, leading to emphysema.
Step 2: Analyzing the options.
(A) In treatment of emphysema: Correct — Patients with alpha-1-antitrypsin deficiency are treated with this protein to prevent lung damage.
(B) In treatment of asthma: Incorrect — Asthma is unrelated to this protein therapy.
(C) As insecticidal protein: Incorrect — Insecticidal proteins are derived from Bacillus thuringiensis, not alpha-1-antitrypsin.
(D) In treatment of diabetes: Incorrect — Diabetes treatment does not involve this protein.
Step 3: Conclusion.
Thus, alpha-1-antitrypsin is used in the treatment of emphysema.