Question:
Which of the following lipoproteins does not move towards the charged end in electrophoresis?
Which of the following lipoproteins does not move towards the charged end in electrophoresis?
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The biggest, most fat-laden particle stays at the start line.
Updated On: Jun 24, 2026
- VLDL
- LDL
- HDL
- Chylomicrons
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Verified By Collegedunia
The Correct Option is D
Solution and Explanation
Step 1: On lipoprotein electrophoresis the particles separate by their net charge and size. Migration position gives each class its alternative Greek-letter name.
Step 2: HDL is the most charged and moves fastest, taking the alpha position. VLDL moves to the pre-beta position. LDL moves to the beta position. All three migrate away from the origin towards the charged (anode) end.
Step 3: Chylomicrons are huge, triglyceride-rich and have very little protein relative to their size, so they have very low surface charge and a high mass. They essentially do not migrate and stay at the point of application (the origin).
Step 4: Therefore the lipoprotein that does not move towards the charged end is the chylomicron.
Answer: Option D (Chylomicrons).
Step 2: HDL is the most charged and moves fastest, taking the alpha position. VLDL moves to the pre-beta position. LDL moves to the beta position. All three migrate away from the origin towards the charged (anode) end.
Step 3: Chylomicrons are huge, triglyceride-rich and have very little protein relative to their size, so they have very low surface charge and a high mass. They essentially do not migrate and stay at the point of application (the origin).
Step 4: Therefore the lipoprotein that does not move towards the charged end is the chylomicron.
Answer: Option D (Chylomicrons).
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