Question:
Which of the following is the least common corneal dystrophy?
Which of the following is the least common corneal dystrophy?
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Rank granular, lattice, and macular by frequency; the rarest deposits mucopolysaccharide.
Updated On: Jun 24, 2026
- Macular dystrophy
- Lattice type I
- Lattice type III
- Granular corneal dystrophy
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The Correct Option is A
Solution and Explanation
Step 1: Among the classic stromal corneal dystrophies, the three to compare are granular, lattice, and macular dystrophy.
Step 2: Granular dystrophy is the most common of the stromal dystrophies, characterised by discrete hyaline deposits that stain with Masson trichrome.
Step 3: Lattice dystrophy is the next, with amyloid deposits forming branching lattice lines that stain with Congo red; the type I form is a well-recognised, relatively frequent variant.
Step 4: Macular dystrophy is the LEAST common of these stromal dystrophies. It is autosomal recessive, deposits glycosaminoglycans (mucopolysaccharide) that stain with Alcian blue and colloidal iron, involves the cornea diffusely up to the limbus, and is the most severe but the rarest.
Step 5: So comparing frequency, granular is commonest, lattice is intermediate, and macular dystrophy is the rarest among the options.
Hence the answer is Option A (Macular dystrophy).
Step 2: Granular dystrophy is the most common of the stromal dystrophies, characterised by discrete hyaline deposits that stain with Masson trichrome.
Step 3: Lattice dystrophy is the next, with amyloid deposits forming branching lattice lines that stain with Congo red; the type I form is a well-recognised, relatively frequent variant.
Step 4: Macular dystrophy is the LEAST common of these stromal dystrophies. It is autosomal recessive, deposits glycosaminoglycans (mucopolysaccharide) that stain with Alcian blue and colloidal iron, involves the cornea diffusely up to the limbus, and is the most severe but the rarest.
Step 5: So comparing frequency, granular is commonest, lattice is intermediate, and macular dystrophy is the rarest among the options.
Hence the answer is Option A (Macular dystrophy).
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