Question:

Which of the following is involved in the transfer of amino acids from cytoplasm to the ribosome for protein synthesis ?

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Aminoacyl-tRNA synthetases are highly precise enzymes that covalently link each amino acid to its corresponding tRNA molecule, a process called tRNA charging.
  • mRNA
  • rRNA
  • tRNA
  • siRNA
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The Correct Option is C

Solution and Explanation

Step 1: Understanding the Concept:
Protein translation is the process of synthesizing a polypeptide chain from an mRNA template.
This process requires different types of RNA molecules to coordinate the assembly of amino acids.

Step 2: Detailed Explanation:

Let us analyze the role of each RNA molecule in translation:
1. tRNA (Transfer RNA): This small RNA molecule serves as an adapter.
Each tRNA has a specific anticodon loop that recognizes a complementary codon on the mRNA, and a 3' acceptor stem where a specific amino acid is covalently attached.
During translation, the tRNA captures its specific amino acid in the cytoplasm and delivers it directly to the active site of the ribosome, aligning it with the mRNA codon.
Thus, tRNA is directly responsible for transporting amino acids.
2. mRNA (Messenger RNA): This template molecule carries the genetic sequence transcribed from DNA, specifying the amino acid sequence of the protein.
3. rRNA (Ribosomal RNA): This structural and catalytic RNA forms the core of the ribosome, facilitating peptide bond formation.
4. siRNA (Small Interfering RNA): This regulatory RNA is involved in post-transcriptional gene silencing, not translation elongation.

Step 3: Final Answer:

The RNA molecule responsible for transferring amino acids is tRNA, corresponding to option (C).
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