Question:
Which of the following is a non-systemic antacid?
Which of the following is a non-systemic antacid?
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Antacids are divided into systemic and non-systemic types. A systemic antacid is absorbed into the blood and can upset the body's acid-base balance, while a non-systemic antacid stays mostly in the gut and does not.
Updated On: Jun 24, 2026
- Sodium Bicarbonate
- Potassium citrate
- Magnesium hydroxide
- Sodium citrate
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The Correct Option is C
Solution and Explanation
Concept:
Antacids are divided into systemic and non-systemic types. A systemic antacid is absorbed into the blood and can upset the body's acid-base balance, while a non-systemic antacid stays mostly in the gut and does not.
Step 1: Magnesium hydroxide reacts with stomach acid to form magnesium chloride and water. The magnesium is poorly absorbed, so it acts locally in the stomach and intestine.
Step 2: Because it is not absorbed into the bloodstream, it does not cause systemic alkalosis — making it a non-systemic antacid.
Why the others are wrong: Sodium bicarbonate, potassium citrate and sodium citrate are absorbed into the blood and can raise the body's pH, so they are systemic antacids/alkalinisers. Only magnesium hydroxide acts non-systemically.
Answer: Option (3) — Magnesium hydroxide.
Antacids are divided into systemic and non-systemic types. A systemic antacid is absorbed into the blood and can upset the body's acid-base balance, while a non-systemic antacid stays mostly in the gut and does not.
Step 1: Magnesium hydroxide reacts with stomach acid to form magnesium chloride and water. The magnesium is poorly absorbed, so it acts locally in the stomach and intestine.
Step 2: Because it is not absorbed into the bloodstream, it does not cause systemic alkalosis — making it a non-systemic antacid.
Why the others are wrong: Sodium bicarbonate, potassium citrate and sodium citrate are absorbed into the blood and can raise the body's pH, so they are systemic antacids/alkalinisers. Only magnesium hydroxide acts non-systemically.
Answer: Option (3) — Magnesium hydroxide.
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