Step 1: The CDC classifies bioterrorism agents into Category A, B and C based on ease of spread and impact. Category A agents pose the highest risk, being easily disseminated, causing high mortality and major public health impact.
Step 2: Category A includes anthrax (Bacillus anthracis), plague, smallpox, botulism, tularemia and the viral haemorrhagic fevers. Anthrax is a classic Category A agent, so option d fits.
Step 3: Q fever, typhus fever and Brucella are all Category B agents, which are moderately easy to disseminate and cause lower mortality. They do not belong to Category A.
Step 4: The correct answer is option 4, Anthrax.