Question:
Which of the following conditions is NOT caused by Parvovirus B19?
Which of the following conditions is NOT caused by Parvovirus B19?
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Roseola is HHV-6/7, not parvovirus B19.
Updated On: Jun 24, 2026
- Roseola infantum
- Aplastic anaemia in sickle cell disease
- Fetal hydrops
- Erythema infectiosum
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The Correct Option is A
Solution and Explanation
Step 1: Parvovirus B19 has a tropism for erythroid progenitor cells, so its diseases revolve around red cell production and rash. Step 2: In patients with chronic haemolysis such as sickle cell disease, B19 halts erythropoiesis and causes a transient aplastic crisis (option b is caused by B19). In pregnancy, transplacental infection in the first 20 weeks can cause profound fetal anaemia leading to hydrops fetalis (option c is caused by B19). Step 3: B19 also causes erythema infectiosum (fifth disease), the classic slapped-cheek rash of childhood (option d is caused by B19). Step 4: Roseola infantum (exanthem subitum, sixth disease) is caused by human herpesvirus 6 (and 7), not parvovirus B19. Therefore the condition NOT caused by B19 is roseola infantum, so option a is correct.
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