Question:
Which metal results in "saturnine gout" formation?
Which metal results in "saturnine gout" formation?
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The word saturnine is the old alchemical name for one specific metal.
Updated On: Jun 23, 2026
- Cadmium
- Lead
- Beryllium
- Mercury
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The Correct Option is B
Solution and Explanation
Step 1: Saturnine gout is a rheumatologic manifestation of chronic lead poisoning. The term "saturnine" derives from Saturn, the alchemical name for lead.
Step 2: Lead impairs purine metabolism and reduces renal excretion of uric acid, leading to hyperuricaemia and gouty arthritis.
Step 3: A classic source is illicitly distilled alcohol (moonshine) contaminated with lead from the apparatus, plus old lead plumbing and paints.
Step 4: Cadmium causes itai-itai disease and renal tubular damage, beryllium causes berylliosis, and mercury causes neurological and renal toxicity, none of which produces saturnine gout. Hence the metal is lead.
Step 2: Lead impairs purine metabolism and reduces renal excretion of uric acid, leading to hyperuricaemia and gouty arthritis.
Step 3: A classic source is illicitly distilled alcohol (moonshine) contaminated with lead from the apparatus, plus old lead plumbing and paints.
Step 4: Cadmium causes itai-itai disease and renal tubular damage, beryllium causes berylliosis, and mercury causes neurological and renal toxicity, none of which produces saturnine gout. Hence the metal is lead.
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