Question

Which is the first cell to reach site of infection

• A. Neutrophils
• B. Eosinophils
• C. Basophils
• D. Macrophages

Hint:

Think of neutrophils as the first responders of the immune system, arriving rapidly to contain the initial threat.

Answer 1

The Correct Option is A

Step 1: Understanding the Concept:
The inflammatory response is the initial protective reaction of the innate immune system to tissue injury or pathogens.

Step 2: Detailed Explanation:
Upon tissue damage or pathogen invasion, chemical signals (chemokines) are released to recruit white blood cells.
Neutrophils (highly active polymorphonuclear granulocytes in fish) are highly motile and are the very first leukocytes to migrate through blood vessel walls to the site of infection.
They engulf pathogens via phagocytosis and release antimicrobial enzymes and reactive oxygen species.
Macrophages arrive later to clear cellular debris and continue phagocytosis.

Step 3: Final Answer:
Neutrophils are the first immune cells recruited to the site of acute infection.