Question:

Which cells are primarily involved in cell-mediated adaptive immunity?

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Adaptive (acquired) immunity has two arms: humoral immunity, which works through antibodies, and cell-mediated immunity, which works through direct cell action.
Updated On: Jun 24, 2026
  • B-cells
  • Thrombocytes
  • Mast cells
  • T-cells
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The Correct Option is D

Solution and Explanation

Concept:
Adaptive (acquired) immunity has two arms: humoral immunity, which works through antibodies, and cell-mediated immunity, which works through direct cell action. We need to identify the cell type that drives the cell-mediated arm.

Step 1: T-cells (T-lymphocytes) are the central players in cell-mediated immunity. Helper T-cells coordinate the response and cytotoxic T-cells directly kill virus-infected and abnormal cells. This is the hallmark of the cell-mediated response.

Step 2: The others don't fit — B-cells run the humoral (antibody) arm, thrombocytes (platelets) are for blood clotting, and mast cells are involved in allergy and inflammation, not cell-mediated adaptive immunity.

Answer: Option (4) — T-cells are primarily involved in cell-mediated adaptive immunity. (4)
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