Question

What is true about Autophagy?

• A. \( \text{Can be considered a cell survival pathway as well as a cell death pathway} \)
• B. \( \text{Might be activated when AMP-dependent kinase (AMPK) is inhibited} \)
• C. \( \text{Could release branched-chain amino acids from muscle} \)
• D. \( \text{Is associated with movement of phosphatidyl serine to the outer leaflet} \)

Hint:

Autophagy dysfunction is linked to various diseases, including neurodegenerative disorders and cancer.

Answer 1

The Correct Option is A

Autophagy is a cellular process responsible for degrading and recycling intracellular components. It plays a dual role in cell survival under nutrient starvation and cell death under pathological conditions. Autophagy is tightly regulated and essential for maintaining cellular homeostasis.