Question

What is the function of Sertoli cells in human testes?

Hint:

Sertoli cells are often referred to as "nurse cells" because of their essential role in supporting and regulating the development of sperm cells in the testes.

Answer 1

Step 1: Sertoli cells are specialized cells found in the seminiferous tubules of the testes. They play a crucial role in supporting and nourishing the developing sperm cells.
Step 2: The functions of Sertoli cells include:
1. Providing physical support to developing sperm cells (spermatogenesis).
2. Secreting nutrients and hormones (such as inhibin) that regulate sperm production.
3. Forming the blood-testis barrier, which prevents harmful substances from reaching the developing sperm.
Step 3: Sertoli cells also help in the regulation of the immune response in the testes and protect sperm from the body's immune system.
Additionally, they are involved in the secretion of fluid that helps in the transport of sperm cells.