Question:
What is the amount of diphtheria toxoid present in the pediatric DT vaccine?
What is the amount of diphtheria toxoid present in the pediatric DT vaccine?
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Pediatric DT is full strength; adult dT drops to about 2 Lf.
Updated On: Jun 24, 2026
- 5 Lf
- 10 Lf
- 15 Lf
- 25 Lf
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The Correct Option is D
Solution and Explanation
Step 1: Diphtheria toxoid content is measured in flocculation units (Lf). The amount differs between the pediatric and the adult formulations.
Step 2: The ordinary pediatric DPT and DT vaccines contain 25 Lf of diphtheria toxoid, so for the pediatric DT asked here the answer is 25 Lf. (Ref: Park, 22nd edition, p. 153)
Step 3: For immunising adults and older children above 12 years, the low-dose adult preparation dT is used, which contains only about 2 Lf of diphtheria toxoid. The smaller dose reduces reactions in people who are already partly primed.
Step 4: Additional points on DPT: it protects against diphtheria, tetanus and pertussis; the killed pertussis component boosts the potency of the diphtheria toxoid; aluminium salts act as adjuvant; thiomersal is the preservative; it is stored at +2 to +8 degrees C and must never be frozen. Hence the pediatric value is 25 Lf.
Step 2: The ordinary pediatric DPT and DT vaccines contain 25 Lf of diphtheria toxoid, so for the pediatric DT asked here the answer is 25 Lf. (Ref: Park, 22nd edition, p. 153)
Step 3: For immunising adults and older children above 12 years, the low-dose adult preparation dT is used, which contains only about 2 Lf of diphtheria toxoid. The smaller dose reduces reactions in people who are already partly primed.
Step 4: Additional points on DPT: it protects against diphtheria, tetanus and pertussis; the killed pertussis component boosts the potency of the diphtheria toxoid; aluminium salts act as adjuvant; thiomersal is the preservative; it is stored at +2 to +8 degrees C and must never be frozen. Hence the pediatric value is 25 Lf.
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