Question:

UDP-glucose is NOT used in?

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Which pathway runs straight from glucose-6-phosphate to make NADPH?
Updated On: Jun 24, 2026
  • Uronic acid pathway
  • Glycogen synthesis
  • Galactose metabolism
  • HMP shunt
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The Correct Option is D

Solution and Explanation

Step 1: UDP-glucose is the activated form of glucose. It is made from glucose-6-phosphate, which is converted to glucose-1-phosphate and then to UDP-glucose.

Step 2: Its main fate is glycogen synthesis (option b), where it donates glucose units to the growing glycogen chain. It also feeds the uronic acid pathway to make UDP-glucuronate (option a) and takes part in galactose metabolism (option c) and in the glycosylation of proteins, lipids and proteoglycans.

Step 3: The HMP shunt (hexose monophosphate pathway) starts directly from glucose-6-phosphate and uses no UDP-glucose. Its job is to generate NADPH and ribose-5-phosphate.

Step 4: Since UDP-glucose plays no part in the HMP shunt, option d is the correct answer to a question asking where it is NOT used.
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