Question:
Type E adverse reaction is?
Type E adverse reaction is?
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E for End of use - reaction on stopping the drug.
Updated On: Jun 24, 2026
- Toxicity
- Augmented effect
- Teratogenesis
- Withdrawal reaction
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The Correct Option is D
Solution and Explanation
Step 1: Adverse drug reactions are classified into types A through E. Type E stands for End of use, that is reactions that appear when a drug is stopped, so the answer is withdrawal reaction.
Step 2: A classic example is the rebound hypertension seen on abrupt withdrawal of clonidine. Other examples include withdrawal seizures after stopping benzodiazepines or alcohol.
Step 3: Why the others are wrong - augmented effect is Type A (dose related extension of pharmacology, such as postural hypotension or hypoglycemia). Teratogenesis and carcinogenesis are Type D (Delayed) reactions. Toxicity in general falls under the dose related Type A category, not Type E.
Answer: Withdrawal reaction.
Step 2: A classic example is the rebound hypertension seen on abrupt withdrawal of clonidine. Other examples include withdrawal seizures after stopping benzodiazepines or alcohol.
Step 3: Why the others are wrong - augmented effect is Type A (dose related extension of pharmacology, such as postural hypotension or hypoglycemia). Teratogenesis and carcinogenesis are Type D (Delayed) reactions. Toxicity in general falls under the dose related Type A category, not Type E.
Answer: Withdrawal reaction.
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