Question:
Type B adverse drug reaction is -
Type B adverse drug reaction is -
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A to E: A is Augmented, B is Bizarre, C is Chronic, D is Delayed, E is End-of-use.
Updated On: Jun 24, 2026
- Augmented effect of drug
- Unpredictable bizarre reaction
- Effect seen on chronic use of drug
- Delayed effect of drug
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The Correct Option is B
Solution and Explanation
Step 1: Adverse drug reactions (ADRs) are classified by the DoTS or the A to E mnemonic. The letters stand for Augmented (A), Bizarre (B), Chronic (C), Delayed (D) and End-of-use (E).
Step 2: Type B reactions are Bizarre. They are unpredictable, not related to the known pharmacology of the drug, and not dose dependent. Examples include hypersensitivity and idiosyncratic reactions such as penicillin anaphylaxis or halothane hepatitis.
Step 3: So the correct answer is the unpredictable bizarre reaction.
Step 4: Why the others are wrong: an augmented effect is Type A (dose dependent and predictable, like bradycardia with a beta blocker); an effect on chronic use is Type C (for example HPA axis suppression with long-term steroids); a delayed effect is Type D (such as carcinogenesis or teratogenesis).
Step 2: Type B reactions are Bizarre. They are unpredictable, not related to the known pharmacology of the drug, and not dose dependent. Examples include hypersensitivity and idiosyncratic reactions such as penicillin anaphylaxis or halothane hepatitis.
Step 3: So the correct answer is the unpredictable bizarre reaction.
Step 4: Why the others are wrong: an augmented effect is Type A (dose dependent and predictable, like bradycardia with a beta blocker); an effect on chronic use is Type C (for example HPA axis suppression with long-term steroids); a delayed effect is Type D (such as carcinogenesis or teratogenesis).
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