Question:
TRALI (transfusion-related acute lung injury) occurs within how many hours of transfusion?
TRALI (transfusion-related acute lung injury) occurs within how many hours of transfusion?
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Acute lung injury defined by onset within a short single-digit window after transfusion.
Updated On: Jun 24, 2026
- 48 hours
- 72 hours
- 6 hours
- 12 hours
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The Correct Option is C
Solution and Explanation
Step 1: Transfusion-Related Acute Lung Injury (TRALI) is an acute respiratory distress syndrome that develops during or shortly after a blood transfusion. Step 2: By definition the onset is within 6 hours of transfusion, so the correct option is 6 hours. Step 3: It presents with rapid dyspnoea, tachypnoea, fever, cyanosis and hypotension, with bilateral non-cardiogenic pulmonary oedema on the chest X-ray (white-out) and no signs of circulatory overload or CHF. Step 4: The longer windows of 12, 48 or 72 hours do not match the accepted definition, which fixes the cut-off at 6 hours.
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