Step 1: Recall how the lung volumes fit together.
Vital capacity (VC) is the total air a person can move in a single breath, from a full inhale to a full exhale. It is made up of three smaller volumes added together: the tidal volume (TV, the air moved in normal quiet breathing), the inspiratory reserve volume (IRV, the extra air you can pull in beyond a normal breath), and the expiratory reserve volume (ERV, the extra air you can push out beyond a normal breath).
\[ VC = TV + IRV + ERV \]
Step 2: Fill in the known values.
\[ VC = 4600 \text{ mL}, \quad TV = 500 \text{ mL}, \quad IRV = 2500 \text{ mL} \]
Step 3: Solve for the expiratory reserve volume.
\[ ERV = VC - TV - IRV \]
\[ ERV = 4600 - 500 - 2500 \]
\[ ERV = 4600 - 3000 = 1600 \text{ mL} \]
Step 4: Sanity check.
Adding the three parts back gives \(500 + 2500 + 1600 = 4600\) mL, which matches the given vital capacity, so the value is consistent.
Final Answer:
The expiratory reserve volume is 1600 mL. \[ \boxed{ERV = 1600 \text{ mL}} \]