Question:

The purpose of DEC provocation test in filariasis assessment is to:

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DEC Provocation = "Provoking" the worms to come out during the day.
Updated On: May 25, 2026
  • Destroy adult worms in the body
  • Detect antibodies against filarial parasites
  • Induce microfilariae in peripheral blood for detection
  • Produce immunity against filariasis
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The Correct Option is C

Solution and Explanation

Step 1: Concept
Filariasis diagnosis often depends on detecting microfilariae, which usually exhibit nocturnal periodicity (appearing in blood only at night).

Step 2: Meaning

The DEC (Diethylcarbamazine) provocation test is used when night-time blood sampling is not feasible.

Step 3: Analysis

A small dose of DEC causes the microfilariae to temporarily migrate from the deep pulmonary vessels into the peripheral circulation during the daytime.

Step 4: Conclusion

This facilitates the detection of the parasite during regular clinic hours. Final Answer: (C)
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