Question:
The phenomenon by which cancer cells are able to sustain and proliferate under adverse conditions of hypoxia is?
The phenomenon by which cancer cells are able to sustain and proliferate under adverse conditions of hypoxia is?
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Named after the scientist who described aerobic glycolysis in tumours.
Updated On: Jun 24, 2026
- Warburg
- Wanton
- Wormian
- Wolf
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The Correct Option is A
Solution and Explanation
Step 1: The question asks about the metabolic adaptation that lets tumour cells survive low-oxygen conditions. This is the Warburg phenomenon, described by Otto Warburg.
Step 2: Cancer cells preferentially use aerobic glycolysis (converting glucose to lactate) even when oxygen is available. This shift in bioenergetics and metabolism permits the cells to grow despite hypoxia and supports proliferation, progression, invasiveness, and distant metastasis.
Step 3: Because it actively promotes tumour growth, it is called the growth-promoting Warburg phenomenon (or Warburg effect).
Step 4: The other terms are distractors. Wormian refers to small extra bones in skull sutures, Wolffian relates to embryology, and Wanton is not a recognised oncology term. Hence Warburg is correct.
Step 2: Cancer cells preferentially use aerobic glycolysis (converting glucose to lactate) even when oxygen is available. This shift in bioenergetics and metabolism permits the cells to grow despite hypoxia and supports proliferation, progression, invasiveness, and distant metastasis.
Step 3: Because it actively promotes tumour growth, it is called the growth-promoting Warburg phenomenon (or Warburg effect).
Step 4: The other terms are distractors. Wormian refers to small extra bones in skull sutures, Wolffian relates to embryology, and Wanton is not a recognised oncology term. Hence Warburg is correct.
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