First, calculate the expression \( 13 \times 16^3 + 11 \times 16^2 + 9 \times 16 + 3 \). This gives us:
\[
13 \times 16^3 + 11 \times 16^2 + 9 \times 16 + 3 = 13 \times 4096 + 11 \times 256 + 9 \times 16 + 3 = 53248 + 2816 + 144 + 3 = 56111
\]
Now, convert \( 56111 \) to its binary representation:
\[
56111_{10} = 1101101011011111_2
\]
There are 10 ones in the binary representation.
Thus, the number of 1's in the binary representation is \( 10 \).