Question:

The most common neoplasm in patients with AIDS is:

Updated On: Jul 14, 2026
  • Carcinoma of breast
  • Acute myeloid leukaemia
  • Adenocarcinoma
  • Kaposi sarcoma
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The Correct Option is D

Approach Solution - 1

The correct option is (D): Kaposi sarcoma .
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Approach Solution -2

The question asks for the most common neoplasm seen in patients with AIDS. Let's check each of the listed cancers.

  1. Carcinoma of breast: Breast carcinoma is a common cancer in the general population but is not the malignancy classically associated with, or increased in frequency by, AIDS-related immunosuppression.
  2. Acute myeloid leukaemia: This blood cancer occurs in the general population and is not specifically linked to HIV/AIDS as its most characteristic neoplasm.
  3. Adenocarcinoma: This is a broad, general term for cancers arising from glandular tissue and covers many different cancer types across the body. It is not the specific, well recognized AIDS-defining malignancy that the question is looking for.
  4. Kaposi sarcoma: This is a vascular tumor caused by human herpesvirus 8 (HHV-8) infection, which becomes far more aggressive and common when the immune system is severely weakened, as happens in advanced HIV infection. It is one of the classic AIDS-defining illnesses and is recognized as the most common AIDS-associated neoplasm.

Kaposi sarcoma stands apart from the other three cancers listed because it is directly driven by an opportunistic viral infection that flourishes specifically under the immunosuppression caused by AIDS.

Therefore, the correct answer is Kaposi sarcoma.

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