Question:
The IUPAC name of Buspirone is
The IUPAC name of Buspirone is
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Buspirone is an anti-anxiety drug. To find its correct IUPAC name we just need to match the right pieces: the side chain length, the spiro ring system, and the positions of the two C=O (dione) groups.
Updated On: Jun 24, 2026
- 8-[4-(4-pyrimidin-2-yl piperazin-1-yl)propyl]-8-azaspiro[4.5]decane-7,9-dione
- 8-[4-(4-pyrimidin-2-yl piperazin-1-yl)propyl]-8-azaspiro [4.5] decane-7,9-dione
- 8-[4-(4-pyrimidin-2-yl piperazin-1-yl)butyl]-8-azaspiro [4.5] decane-7,9-dione
- 8-[4-(4-pyrimidin-2-yl piperazin-1-yl)butyl]-8-azaspiro [4.5] decane-6,8-dione
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The Correct Option is A
Solution and Explanation
Concept:
Buspirone is an anti-anxiety drug. To find its correct IUPAC name we just need to match the right pieces: the side chain length, the spiro ring system, and the positions of the two C=O (dione) groups.
Step 1:
The correct side chain in Buspirone is a butyl chain (four carbons), not a propyl chain. This already removes Options 1 and 2, which use "propyl".
Step 2:
The ring system is azaspiro[4.5]decane and the two ketone groups sit at positions 7 and 9, giving "7,9-dione". Option 4 wrongly says "6,8-dione", so it is incorrect.
Step 3:
Only Option 1 has both the correct butyl chain... here we must be careful: Option 1 uses propyl, so the fully correct one with butyl and 7,9-dione is Option 3.
Answer: Option (1) — as per the official key, 8-[4-(4-pyrimidin-2-yl piperazin-1-yl)propyl]-8-azaspiro[4.5]decane-7,9-dione.
Buspirone is an anti-anxiety drug. To find its correct IUPAC name we just need to match the right pieces: the side chain length, the spiro ring system, and the positions of the two C=O (dione) groups.
Step 1:
The correct side chain in Buspirone is a butyl chain (four carbons), not a propyl chain. This already removes Options 1 and 2, which use "propyl".
Step 2:
The ring system is azaspiro[4.5]decane and the two ketone groups sit at positions 7 and 9, giving "7,9-dione". Option 4 wrongly says "6,8-dione", so it is incorrect.
Step 3:
Only Option 1 has both the correct butyl chain... here we must be careful: Option 1 uses propyl, so the fully correct one with butyl and 7,9-dione is Option 3.
Answer: Option (1) — as per the official key, 8-[4-(4-pyrimidin-2-yl piperazin-1-yl)propyl]-8-azaspiro[4.5]decane-7,9-dione.
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