Question:

The dose of diphtheria antitoxin (DAT) is:

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DAT comes in 10,000 IU ampoules and dosing scales up with severity.
Updated On: Jun 23, 2026
  • 1000 to 5000 IU
  • 10000 to 100000 IU
  • 1000 to 2000 IU
  • None
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The Correct Option is B

Solution and Explanation

Step 1: Diphtheria antitoxin (DAT) is a horse-serum based passive immunising agent given to neutralise circulating diphtheria toxin.
Step 2: It is supplied in ampoules of about 10,000 IU each, and clinical dosing is built up in this range depending on the site and severity of the disease.
Step 3: The total therapeutic dose used in practice ranges from roughly 10,000 IU up to about 100,000 IU.
Step 4: Among the options, the 10,000 to 100,000 IU band matches the recognised dose, so it is the correct choice.
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